The Role of Polyunsaturated ω-3 Fatty Acid Eicosapentaenoic Acid–Derived Resolvin E1 (RvE1) in Bone Preservation
Identifieur interne : 001667 ( Main/Exploration ); précédent : 001666; suivant : 001668The Role of Polyunsaturated ω-3 Fatty Acid Eicosapentaenoic Acid–Derived Resolvin E1 (RvE1) in Bone Preservation
Auteurs : Robert Gyurko [États-Unis] ; Thomas E. Van Dyke [États-Unis]Source :
- Critical reviews in immunology [ 1040-8401 ] ; 2014.
Abstract
Resolvin E1 (RvE1) is a recently discovered lipid-derived mediator that is endogenously synthesized from the polyunsaturated fatty acid eicosapentaenoic acid. RvE1 is locally generated in response to inflammation where it enhances the resolution phase of inflammation by diminishing neutrophil chemotaxis and by enhancing nonphlogistic macrophage-directed clearance of apoptotic neutrophils. RvE1 was also found to be effective in preventing and restoring bone loss in the inflammatory bone disease periodontitis. This review examines experimental evidence on RvE1's actions in bone. Current data indicate that in addition to anti-inflammatory actions, RvE1 also directly acts on bone cells and promotes bone preservation.
Url:
PubMed: 24941160
PubMed Central: 4382917
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 002752
- to stream Pmc, to step Curation: 002752
- to stream Pmc, to step Checkpoint: 001174
- to stream Ncbi, to step Merge: 005186
- to stream Ncbi, to step Curation: 005186
- to stream Ncbi, to step Checkpoint: 005186
- to stream Main, to step Merge: 001670
- to stream Main, to step Curation: 001667
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Role of Polyunsaturated ω-3 Fatty Acid Eicosapentaenoic Acid–Derived Resolvin E1 (RvE1) in Bone Preservation</title>
<author><name sortKey="Gyurko, Robert" sort="Gyurko, Robert" uniqKey="Gyurko R" first="Robert" last="Gyurko">Robert Gyurko</name>
<affiliation wicri:level="2"><nlm:aff id="A1">Department of Periodontology, Boston University, Boston, Massachusetts</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Periodontology, Boston University, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Van Dyke, Thomas E" sort="Van Dyke, Thomas E" uniqKey="Van Dyke T" first="Thomas E." last="Van Dyke">Thomas E. Van Dyke</name>
<affiliation wicri:level="2"><nlm:aff id="A2">The Forsyth Institute, Cambridge, Massachusetts</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>The Forsyth Institute, Cambridge</wicri:cityArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">24941160</idno>
<idno type="pmc">4382917</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382917</idno>
<idno type="RBID">PMC:4382917</idno>
<date when="2014">2014</date>
<idno type="wicri:Area/Pmc/Corpus">002752</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002752</idno>
<idno type="wicri:Area/Pmc/Curation">002752</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002752</idno>
<idno type="wicri:Area/Pmc/Checkpoint">001174</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001174</idno>
<idno type="wicri:Area/Ncbi/Merge">005186</idno>
<idno type="wicri:Area/Ncbi/Curation">005186</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">005186</idno>
<idno type="wicri:doubleKey">1040-8401:2014:Gyurko R:the:role:of</idno>
<idno type="wicri:Area/Main/Merge">001670</idno>
<idno type="wicri:Area/Main/Curation">001667</idno>
<idno type="wicri:Area/Main/Exploration">001667</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Role of Polyunsaturated ω-3 Fatty Acid Eicosapentaenoic Acid–Derived Resolvin E1 (RvE1) in Bone Preservation</title>
<author><name sortKey="Gyurko, Robert" sort="Gyurko, Robert" uniqKey="Gyurko R" first="Robert" last="Gyurko">Robert Gyurko</name>
<affiliation wicri:level="2"><nlm:aff id="A1">Department of Periodontology, Boston University, Boston, Massachusetts</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Periodontology, Boston University, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Van Dyke, Thomas E" sort="Van Dyke, Thomas E" uniqKey="Van Dyke T" first="Thomas E." last="Van Dyke">Thomas E. Van Dyke</name>
<affiliation wicri:level="2"><nlm:aff id="A2">The Forsyth Institute, Cambridge, Massachusetts</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>The Forsyth Institute, Cambridge</wicri:cityArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Critical reviews in immunology</title>
<idno type="ISSN">1040-8401</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">Resolvin E1 (RvE1) is a recently discovered lipid-derived mediator that is endogenously synthesized from the polyunsaturated fatty acid eicosapentaenoic acid. RvE1 is locally generated in response to inflammation where it enhances the resolution phase of inflammation by diminishing neutrophil chemotaxis and by enhancing nonphlogistic macrophage-directed clearance of apoptotic neutrophils. RvE1 was also found to be effective in preventing and restoring bone loss in the inflammatory bone disease periodontitis. This review examines experimental evidence on RvE1's actions in bone. Current data indicate that in addition to anti-inflammatory actions, RvE1 also directly acts on bone cells and promotes bone preservation.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Massachusetts</li>
</region>
</list>
<tree><country name="États-Unis"><region name="Massachusetts"><name sortKey="Gyurko, Robert" sort="Gyurko, Robert" uniqKey="Gyurko R" first="Robert" last="Gyurko">Robert Gyurko</name>
</region>
<name sortKey="Van Dyke, Thomas E" sort="Van Dyke, Thomas E" uniqKey="Van Dyke T" first="Thomas E." last="Van Dyke">Thomas E. Van Dyke</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001667 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001667 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= EdenteV2 |flux= Main |étape= Exploration |type= RBID |clé= PMC:4382917 |texte= The Role of Polyunsaturated ω-3 Fatty Acid Eicosapentaenoic Acid–Derived Resolvin E1 (RvE1) in Bone Preservation }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:24941160" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a EdenteV2
This area was generated with Dilib version V0.6.32. |